That microRNA-294 (mir-294) beneficially affects heart regeneration was discovered via its presence in embryonic stem cell exosomes. Exosomes are extracellular vesicles, membrane-bound packages of molecules that cells pass between one another. They are interesting to the research community because it is in principle much easier to construct a therapy based on delivery of exosomes harvested from stem cells than it is to deliver those same stem cells. Thus most of the present generation of stem cell therapies may well be replaced in the near future by the delivery of extracellular vesicles, and many research groups are testing exosomes from stem cells to see how well they work to spur greater regeneration. Most vesicles contain a wide variety of molecules, but in the case of embryonic
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https://healthnews010.tumblr.com/post/185856133648
From https://johnher1.blogspot.com/2019/06/mir-294-awakens-embryonic-proliferation.html
from
https://johnher1.wordpress.com/2019/06/26/mir-294-awakens-an-embryonic-proliferation-behavior-in-heart-cells-spurring-regeneration-following-heart-attack/
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