More Evidence for Cellular Senescence of β Cells to Drive Type 2 Diabetes

Recently, researchers have demonstrated that senescence of pancreatic β cells is important in both the autoimmunity of type 1 diabetes and the metabolic dysfunction of type 2 diabetes. This was very surprising in the first case, less so in the second, since type 2 diabetes emerges more readily in older individuals. The specific mechanisms by which increased cellular senescence arises in the pancreas is probably different in each case, but the use of senolytic treatments to clear senescent cells has produced significant benefits in animal models of both conditions. This adds to the many other conditions in which targeted removal of senescent cells is a viable therapy. Here, researchers outline more evidence for an important role for cellular senescence in type 2 diabetes. It is compelling. It has to be said

from https://www.fightaging.org/archives/2019/06/more-evidence-for-cellular-senescence-of-β-cells-to-drive-type-2-diabetes/

from
https://healthnews010.tumblr.com/post/185377658448

From https://johnher1.blogspot.com/2019/06/more-evidence-for-cellular-senescence.html

from
https://johnher1.wordpress.com/2019/06/05/more-evidence-for-cellular-senescence-of-%ce%b2-cells-to-drive-type-2-diabetes/